Non-Specific Clotting Factor Inhibitor

Coagulation

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Description

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Sample Type

Plasma (Citrate 2.7ml Blue) x 2

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Reference Range

The inhibitor titre is measured in Bethesda units (BU) with 1 BU being defined as the the titre of inhibitor which will inhibit 50% of total FVIII activity.

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Turnaround Time

Within 2 weeks

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Testing Frequency

weekly or as required

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External Notes

PRIOR ARRANGEMENT WITH HAEMATOLOGY SPR AND LABORATORY IS REQUIRED FOR URGENT REQUESTS. FVIII:C LEVEL IS ALSO REQUIRED FOR ANALYSIS OF FVIII INHIBITOR.

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References

References Verbruggen B et al (1995). The Nijmegen modification of the bethesda assay for FVIII:C inhibitors: improved specificity and reliability. Thromb Haemost. 73, 247-51

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Please note: the above information is subject to change and we endeavour to keep this website up to date wherever necessary.